This DRI program is focused on understanding how genetic and immunological factors play a role in the development of type 1 diabetes and, by contrast, how certain genetic and immunological factors may actually afford protection from diabetes.
Integrating the studies of genetics and immunology of human diabetes, DRI investigators are uncovering ways to interfere with the immune cells that attack the insulin producing cells in the pancreas resulting in diabetes.
This is a critical factor for both preventing and curing diabetes, since the immune cells that caused diabetes in the first place might be reactivated and damage the transplanted insulin-producing cells.
Two major projects in these research areas are the study of Peripheral Antigen Expressing Cells and Recurrence of Autoimmunity in Islet and Pancreas Transplant Recipients.
For more information on participating in these studies, contact us.