Tissue engineering is a broad and rapidly growing field that presents many new opportunities for scientists working in the field of diabetes research.
By combining engineering materials and biochemical factors with cells and other tissue, researchers are designing and developing innovative approaches to maintain, repair and/or replace insulin function.
To bolster its efforts in this area, the DRI has recruited Cherie Stabler, Ph.D., from Emory University School of Medicine to head its expanding tissue engineering program.
Dr. Stabler and her team are working on a number of new approaches to protect transplanted cells from the recipient’s strong immunological and inflammatory responses while providing the critical nutrients needed to sustain healthy function.
The primary areas of focus: the use of alternative transplantation sites and novel biomaterials to house these cells.
>>Bioengineered Devices
Implantable devices that can house and protect transplanted cells.
>>Nanoencapsulation
Encasing, or coating, the transplanted insulin-producing cells with a protective, biocompatible substance.
>>Engineering the Physical Environment
Recreating the cells' "natural" environment -- and providing more oxygen -- to keep cells healthy.