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The Location

Placing a BioHub Within the Body

Currently, islet cells are transplanted into the liver.

But for several reasons, the liver is not an optimal environment. So, DRI scientists and our collaborators worldwide are testing other sites for a BioHub.

One that holds particular promise is the abdomen, specifically the omentum, an apron‐like tissue that covers the abdomen. Researchers are
 creating an abdominal “pouch” by folding over a small section of this tissue. This pouch is rich in blood vessels and may provide a safer and more suitable site.

One of the great advantages of the BioHub is that researchers will know precisely where the islets are placed. This will allow them to retrieve the BioHub, if necessary, to add more islet cells and/or nutrients, protective agents and growth factors. 

The DRI BioHub mini organ mimics the native pancreas
Learn more about the development of the BioHub mini organ to restore natural insulin production in those living with diabetes.
Watch the BioHub video>>

 

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