A World Leader in Diabetes Cure-Focused Research
The Diabetes Research Institute leads the world in cure-focused research. As the largest and most comprehensive research center dedicated to curing diabetes, the DRI is aggressively working to shrink the timeline toward the discovery of a biological cure for this disease.
Since its inception, the DRI has made significant contributions to the field of diabetes, pioneering many of the techniques used in diabetes centers around the world. Having already shown that diabetes can be reversed through islet transplantation, the DRI is building upon these promising outcomes by developing the BioHub, a mini-organ to deliver real insulin in real time. The DRI also collaborates with other leading researchers worldwide to develop and test new approaches to restore natural insulin production.
Pioneering New Therapies to Restore Insulin Production
With the development of the BioHub, the DRI continues its focus on the biological replacement of natural insulin function to restore blood sugar control. DRI scientists have already shown that insulin independence can be achieved through cell replacement strategies. Expert teams continue to make strides in the three over-arching research issues necessary for curing this disease:
1. Sustainability - The immune system – preventing the rejection of donor tissue and reversing the autoimmune attack which caused the onset of diabetes.
2. Supply - of Insulin-Producing Cells – identifying, developing and/or regenerating a limitless supply of cells to sense blood glucose levels and produce insulin.
3. Site - The Optimal Environment -- finding the best spot in the body to place insulin-producing cells.
The Hub of a Global Research Alliance
The DRI has an impressive track record of scientific collaboration and its most far-reaching initiative to date is the Diabetes Research Institute Federation. Researchers from more than 20 medical centers from all corners of the world have agreed to form a one-of-a-kind alliance. This international network of collaborators share knowledge, pool expertise in specific research areas, and apply a diverse set of skills to the eradication of diabetes. The DRI leads this expanding effort with an underlying belief that the best way to make transformative discoveries - in the shortest amount of time – is to work together towards a cure.
For more than 35 consecutive years, DRI scientists have been awarded competitive federal and state grants in the field of diabetes. The resulting discoveries have been published extensively in peer-reviewed journals and many of the DRI’s innovations are in current use at diabetes centers worldwide. As leaders in their respective fields, the Institute’s faculty serves on numerous national and international committees and provides leadership on many scientific review panels and associations.
The Strength of Private Funding
While competitive research grants are the mainstay of world-class research institutes, the Diabetes Research Institute Foundation provides the DRI with critical seed funding to gather data that is often a prerequisite for larger grants. This funding stream is at the heart of DRI’s ability to innovate and make quantum leaps in the race for a cure. Supported by private philanthropy, the DRI Foundation also fills the gaps in many stages of the research process for which there is little federal funding, or for areas in which federal funding falls short of actual need. Driven by its core mission, the DRI Foundation’s support also ensures the body of work conducted at the DRI remains cure-focused and will ultimately benefit those with diabetes.
A Community Resource
The DRI is a designated Center of Excellence at the University of Miami Miller School of Medicine, providing informative education and training programs for many types of health care professionals and industry representatives. For patients with diabetes and their families, the DRI’s Kosow Diabetes Treatment Center offers the highest standards of health care delivery, ongoing management and education support, and numerous clinical research possibilities.
The Best Hope for a Cure
The Diabetes Research Institute was created for one reason – to cure diabetes – which is and will continue to be its singular focus until that goal is reached. With an aggressive approach to curing those living with diabetes, along with its unique spirit of collaboration and notable accomplishments, the DRI is leading the international effort to eradicate this disease. For the millions of people affected by diabetes, the DRI is the best hope for a cure.