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BioHub FAQs

The DRI BioHub mini organ mimics the native pancreas
Learn more about the development of the BioHub mini organ to restore natural insulin production in those living with diabetes.
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The biodegradable scaffold is made using a patient's own plasma together with thrombin, a clinical-grade enzyme. When combined, they create a "sticky gel" that holds the islets in place. The area of the omentum is then folded over and stitched, creating a protective "pouch" around the scaffold mixture.

One of the platforms considered for a DRI BioHub is a bioengineered scaffold made from clinical-grade silicone. 

A DRI BioHub contains real insulin-producing cells plus other cells and agents to provide long term survival and function.
One of the BioHub platforms in testing is a porous, sponge-like material. Thousands of islet cells (red) nestle within the small pores. Critical oxygen generators (blue), helper cells (yellow) and other agents can be added to a BioHub to keep islet cells healthy, protected and able to function long term.

Your generous support is critical to make the DRI BioHub a reality for those living with type 1 diabetes!
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