Learn more about the development of the BioHub mini organ to restore natural insulin production in those living with diabetes.
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The biodegradable scaffold is made using a patient's own plasma together with thrombin, a clinical-grade enzyme. When combined, they create a "sticky gel" that holds the islets in place. The area of the omentum is then folded over and stitched, creating a protective "pouch" around the scaffold mixture.
One of the BioHub platforms in testing is a porous, sponge-like material. Thousands of islet cells (red) nestle within the small pores. Critical oxygen generators (blue), helper cells (yellow) and other agents can be added to a BioHub to keep islet cells healthy, protected and able to function long term.
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