Miller School of Medicine

Cell and Tissue Engineering

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Fibrin gels engineered with pro-angiogenic growth factors promote engraftment of pancreatic islets in extrahepatic sites in mice. Biotechnology and Bioengineering, 2015.

Device design and materials optimization of conformalcoating for islets of Langerhans. PNAS, 2014. 

Bioorthogonal Layer-by-Layer Encapsulation of Pancreatic Islets via Hyperbranched Polymers. ACS Appl. Mater. Interfaces, 2013.

Proangiogenic Hydrogel Within Macroporous Scaffolds Enhance Islet Engraftment in an Extra Hepatic Site. Tissue Engineering: Part A 2013.

Engineering a Local Microenvironment for Pancreatic Islet ReplacementCurrent Opinion in Biotechnology, 2013.

Synthesis of Macroporous Poly(dimethylsiloxane) Scaffolds for Tissue Engineering Applications.  J Biomat Sci Poly Ed, 2013.

Perfluorinated Alginate for Cellular Encapsulation. Journal of Biomedical Materials Research: Part A, 2012.

A Physhiological Pattern of Oxygenation Using Perfluorocarbon-Based Culture Devices Maximizes Pancreatic Islet Viability and Enhances Beta Cell Function. Cell Transplantation, 2012.

Macroporous Three Dimensional PDMS Scaffolds for Extrahepatic Islet Transplantation. Cell Transplantation, 2012

Oxygen: A Master Regulator of Pancreatic Development? Biology of the Cell, 2012

Cell and Organ Bioengineering Technology as Applied to Gastrointestinal Diseases.  GUT, 2012

Preventing hypoxia-induced cell death in beta cells and islets via hydrolytically activated, oxygen-generating biomaterials. PNAS, 2012.

Optimization of Nano-Scale Emulsions: Perfluoro Micellar Solutions for Enhanced Oxygen Transfer in Biomedical Applications. Colloids and Surfaces B: Biointerfaces, 2012.

Complementary Methods for the Determination of Dissolved Oxygen Content in Perfluorocarbon Emulsions and Other SolutionsThe Journal of Physical Chemistry, 2011.

Covalent Stabilization of Alginate Microbeads via Staudinger Ligation: Assessment of Poly(ethylene glycol) and Alginate Cross-linkers. Journal of Biomedical Materials Research: Part A, 2011.

Microencapsulation of islets within alginate/poly(ethylene glycol) gels cross-linked via Staudinger ligation. Acta Biomaterialia, 2011.

Tissue Engineering Approaches to Enhancing Clinical Islet Transplantation. Diabetes Science and Technology, 2010.

Enhanced Oxygenation Promotes Beta Cell Differentiation in VitroStem Cells, 2007.

Instability of miRNA and cDNAs derivatives in RNA preparations. Biochemical and Biophysical Research Communications, 2007.

Reversal of Diabetes by Pancreatic Islet Transplantation into a Subcutaneous, Neovascularized Device. Transplantation, 2006.

Delivery of TAT/PTD-Fused Proteins/Peptides to Islets via Pancreatic Duct. Cell Transplantation, 2005.

Adenoviral Gene Transfer of EPO Confers Cytoprotection to Isolated Pancreatic Islets. Transplantation, 2004.

Delivery of Bcl-XL or its BH4 domain by protein transduction inhibits apoptosis in human islets. BBRC, 2004.

Delivery of Proteins and Peptides into Live Cells by Means of Protein Transduction Domains: Potential Application to Organ and Cell Transplantation. Transplantation, 2004.

Targeted Bone Marrow Radioablation with Samarium-Lexidronam Promotes Allogeneic Hematopoietic Chimerism and Donor-Specific Immunologic Hyporesponsiveness. Transplantation, 2004.

HO-1 fused to a TAT Peptide Transduces and Protects Pancreatic b-cells. BBRC, 2003.

Adeno-Associated Virus Transduction of Islets with Interleukin-4 Results in Impaired Metabolic Function in Syngeneic Marginal Islet Mass Transplantation. Transplantation, 2002.

Proteins Linked to a Protein Transduction Domain Efficiently Transduce Pancreatic Islets. Diabetes, 2001.

 

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