connect with us

Bookmark and Share
Print Friendly and PDF

Helper Cells

Protecting Transplanted Insulin-Producing Cells Naturally

Researchers have discovered certain cells within our body that could help protect transplanted insulin‐producing cells. Among them is a group of adult stem cells known as mesenchymal stem cells (MSCs). MSCs are found throughout the body and develop into cartilage, bone, fat and other tissues.

Several years ago, the DRI discovered that MSCs obtained from bone marrow have unique properties to help the recipient’s body accept the transplant. MSCs can limit inflammation, stimulate blood vessel growth and promote the long‐term function of islets.

The DRI’s immunology and tissue engineering groups are
 co‐transplanting insulin‐producing cells with MSCs 
into one of the BioHub platforms, the bioengineered scaffold, placed within the omental
 pouch, which is part of the abdomen. Early studies show
 that this approach can enhance acceptance and extend the viability of the transplanted insulin‐producing cells.

Researchers also are investigating other “helper” cells that demonstrate similar therapeutic benefits. Among these are endothelial cells, which line blood vessels.

MSC Scaffold
Mesencymal stem cells (MSCs), in red, one of the "helper cells" used in a BioHub, have shown the ability to reduce inflammation and promote long-term survival and function of transplanted islets (blue cluster).


Diabetes Research Institute Foundation
200 S. Park Road, Suite 100
Hollywood, FL 33021
[P]   (954) 964-4040
[TF] (800) 321-3437
[F]   (954) 964-7036

Join Us on FacebookWatch us on YouTubeFollow Us on Twitter

BBB Wise Giving Alliance Accredited Charity  The Diabetes Research Institute Foundation is a Gold Level Participant on the GuideStar Exchange.  The Blue Circle - the global symbol for diabetes

Home | LoginDRInsider Sign Up | Site MapSite Search Contact UsDirectionsRecommended LinksPrivacy and Terms of Use | Mission Statements

© 2016 Diabetes Research Institute Foundation - National Office: 200 S. Park Road, Suite 100, Hollywood, FL 33021 - (954) 964-4040

Miller School of Medicine