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Bioengineering: Encapsulation, Site, Local Drug Delivery


Manganese oxide particles as cytoprotective, oxygen generating agents
Acta Biomaterialia, July 2017


Effects of Composition of Alginate-Polyethylene Glycol Microcapsules and Transplant Site on Encapsulated Islet Graft Outcomes in Mice
Transplantation, May 2017


Bioengineering the Endocrine Pancreas: Intraomental Islet Transplantation Within a Biologic Resorbable Scaffold
Diabetes, May 2016


Fibrin gels engineered with pro-angiogenic growth factors promote engraftment of pancreatic islets in extrahepatic sites in mice
Biotechnology and Bioengineering, 2015.


Device design and materials optimization of conformalcoating for islets of Langerhans
PNAS, 2014.


Bio-orthogonal Layer-by-Layer Encapsulation of Pancreatic Islets via Hyperbranched Polymers
ACS Appl. Mater. Interfaces, 2013.


Proangiogenic Hydrogel Within Macroporous Scaffolds Enhance Islet Engraftment in an Extra Hepatic Site
Tissue Engineering: Part A 2013.


Engineering a Local Microenvironment for Pancreatic Islet Replacement 
Current Opinion in Biotechnology, 2013.


Synthesis of Macroporous Poly(dimethylsiloxane) Scaffolds for Tissue Engineering Applications 
J Biomat Sci Poly Ed, 2013.


Perfluorinated Alginate for Cellular Encapsulation
Journal of Biomedical Materials Research: Part A, 2012.


A Physhiological Pattern of Oxygenation Using Perfluorocarbon-Based Culture Devices Maximizes Pancreatic Islet Viability and Enhances Beta Cell Function
Cell Transplantation, 2012.


Macroporous Three Dimensional PDMS Scaffolds for Extrahepatic Islet Transplantation
Cell Transplantation, 2012


Oxygen: A Master Regulator of Pancreatic Development?
Biology of the Cell, 2012


Cell and Organ Bioengineering Technology as Applied to Gastrointestinal Diseases 
GUT, 2012


Preventing hypoxia-induced cell death in beta cells and islets via hydrolytically activated, oxygen-generating biomaterials
PNAS, 2012.


Optimization of Nano-Scale Emulsions: Perfluoro Micellar Solutions for Enhanced Oxygen Transfer in Biomedical Applications
Colloids and Surfaces B: Biointerfaces, 2012.


Complementary Methods for the Determination of Dissolved Oxygen Content in Perfluorocarbon Emulsions and Other Solutions
The Journal of Physical Chemistry, 2011.


Covalent Stabilization of Alginate Microbeads via Staudinger Ligation: Assessment of Poly(ethylene glycol) and Alginate Cross-linkers
Journal of Biomedical Materials Research: Part A, 2011.


Microencapsulation of islets within alginate/poly(ethylene glycol) gels cross-linked via Staudinger ligation
Acta Biomaterialia, 2011.


Tissue Engineering Approaches to Enhancing Clinical Islet Transplantation
Diabetes Science and Technology, 2010.


Characterization of Pancreatic Ductal Cells in Human Islet Preparations
Laboratory Investigation, 2008.


Enhanced Oxygenation Promotes Beta Cell Differentiation in Vitro
Stem Cells, 2007.


Instability of miRNA and cDNAs derivatives in RNA preparations 
Biochemical and Biophysical Research Communications, 2007.


Reversal of Diabetes by Pancreatic Islet Transplantation into a Subcutaneous, Neovascularized Device
Transplantation, 2006.


Delivery of TAT/PTD-Fused Proteins/Peptides to Islets via Pancreatic Duct
Cell Transplantation, 2005.


Adenoviral Gene Transfer of EPO Confers Cytoprotection to Isolated Pancreatic Islets
Transplantation, 2004.


Delivery of Bcl-XL or its BH4 domain by protein transduction inhibits apoptosis in human islets. 
BBRC, 2004.


Delivery of Proteins and Peptides into Live Cells by Means of Protein Transduction Domains: Potential Application to Organ and Cell Transplantation 
Transplantation, 2004.


Targeted Bone Marrow Radioablation with Samarium-Lexidronam Promotes Allogeneic Hematopoietic Chimerism and Donor-Specific Immunologic Hyporesponsiveness
Transplantation, 2004.


HO-1 fused to a TAT Peptide Transduces and Protects Pancreatic b-cells
BBRC, 2003.


Improved Human Islet Isolation Outcome from Marginal Donors Following Addition of Oxygenated Perfluorocarbon to the Cold-Storage Solution
Transplantation, 2003.


Adeno-Associated Virus Transduction of Islets with Interleukin-4 Results in Impaired Metabolic Function in Syngeneic Marginal Islet Mass Transplantation
Transplantation, 2002.


Proteins Linked to a Protein Transduction Domain Efficiently Transduce Pancreatic Islets
Diabetes
, 2001.

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Immune Tolerance and Autoimmunity

Cell Supply: Alternative Sources and Regeneration

Bioengineering: Encapsulation, Site Development, Local Drug Delivery and more

Islet Biology and Cell Processing